PUBLICATIONS
To read a paper click onto an icon next to the title
Multiple neuronal populations control the eating behavior in Hydra and are responsive to microbial signals
Giez C, Pinkle D, Giencke Y, Wittlieb J, Herbst E, Spratte T, Lachnit T, Klimovich A, Selhuber-Unkel C, Bosch TCG.
Current Biology 2023; 33:1-16. https://doi.org/10.1016/j.cub.2023.10.038
Novel technologies uncover novel "anti"-microbial peptides in Hydra shaping the species-specific microbiome
Klimovich A and Bosch TCG.
Phil Transact B 2023, in press https://doi.org/10.1098/rstb.2023.0058
Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host-microbe associations
Nawroth JC, Giez C, Klimovich A, Kanso E, Bosch TCG.
eLife 2023; 12:e83637
Spontaneously occurring tumors in different wild-derived strains of hydra
Boutry J, Buysse M, Tissot S, ..., Ujvari B, Giraudeau M, Klimovich A, Thomas F, Tökölyi J.
Scientific Reports 2023; 13:7449
The role of DNA methylation in genome defense in Cnidaria and other invertebrates
Ying H, Hayward DC, Klimovich A, ..., Miller DJ.
Molecular Biology and Evolution 2022; 39(2):msac018
Tumors (re)shape biotic interactions within ecosystems: Experimental evidence from the freshwater cnidarian Hydra
Boutry J, Mistral J, Berlioz L, Klimovich A, ..., Thomas F.
Science of the Total Environment 2022; 803:149923
Neurons interact with the microbiome: an evolutionary-informed perspective
Giez C, Klimovich A, Bosch TCG
Neuroforum 2021; 27 (2):89-98
Prototypical pacemaker neurons interact with the resident microbiota
Klimovich A@, Giacomello S, Björklund Å, Faure L, Kaucka M, Giez C, Murillo-Rincon AP, Matt A-S,
Willoweit-Ohl D, Crupi G, de Anda J, Wong GCL, D’Amato M, Adameyko I, Bosch TCG
PNAS 2020; 117 (30):178954-17863
Featured in: Linking neurons to immunity: Lessons from Hydra. Obata Y. and Pachnis V.
PNAS 2020; 117 (33):19624-19626
Ancestral roles of atypical cadherins in planar cell polarity
Brooun M, Klimovich A, Bashkurov M, Pearson BJ, Steele RE, McNeill H
PNAS 2020; 117 (32):19310-1932
Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra
Rathje K, Mortzfeld B, Hoeppner M, Bosch T, Klimovich A@
PLoS Pathog 2020; 16(3): e1008375
Transgenesis in Hydra to characterize gene function and visualize cell behavior
Klimovich A@, Wittlieb J, Bosch TCG
Nat Protoc 2019; 14:2069-2090
Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
Mortzfeld B, Taubenheim J, Klimovich A, Fraune S, Rosenstiel P, Bosch TCG
Nat Comm 2019; 10(1):3257
Apoptosis in Hydra: function of HyBcl-2 like 4 and proteins of the transmembrane BAX inhibitor motif (TMBIM) containing family
Motamedi M, Lindenthal L, Wagner A, Kemper M, Moneer J, Steichele M, Klimovich A, Wittlieb J, Jenewein M, Böttger A. Int J Dev Biol 2019; 63: 259-270
Klimovich A@, Bosch TCG
BioEssays 2018; 40(9):1800060
Rethinking the role of the nervous system: Lessons from the Hydra holobiont
Non-senescent Hydra tolerates severe disturbances in the nuclear lamina
Klimovich A@, Rehm A, Wittlieb J, Herbst E-M, Benavente R, Bosch TCG
Aging (Albany NY) 2018; 10(5): 951
Mortzfeld BM, Taubenheim J, Fraune S, Klimovich AV, Bosch TCG
Front Microbiol 2018; 9:629
Stem cell transcription factor FoxO controls microbiome resilience in Hydra
Real time dynamics of β-catenin expression during Hydra development, regeneration and Wnt signalling activation
Iachetta R, Ambrosone A, Klimovich A, Wittlieb J, Onorato G, Candeo A, D’andrea C, Intartaglia D,
Scotti N, Blasio M, Tino A, Bassi A, Tortiglione C. Int J Dev Biol 2018; 62(4-5): 311-318
Murillo-Rincon AP, Klimovich A, Pemöller E, Taubenheim J, Mortzfeld B, Augustin R, Bosch TCG
Sci Rep 2017; 7(1): 15937
Spontaneous body contractions are modulated by the microbiome of Hydra
Back to the basics: Cnidarians start to fire
Bosch T, Klimovich A, Domazet-Lošo T, Gründer S, Holstein TW, Jékely G, Miller DJ, Murillo-Rincon AP, Rentzsch F, Richards GS, Schröder K, Technau U, Yuste R.
Trends Neurosci 2017; 40(2):92-105
Domazet-Lošo T*, Klimovich A*, Anokhin B, Anton-Erxleben F, Hamm MJ, Lange C, Bosch TCG
Nat Comm 2014; 5:4222
Naturally occurring tumours in the basal metazoan Hydra
Bosch T, Adamska M, Augustin R, Domazet-Lošo T, Foret S, Fraune S, Funayama N, Grasis J, Hamada M, Hatta M, Hobmayer B, Kawai K, Klimovich A, Manuel M, Shinzato C, Technau U, Yum S, Miller DJ
BioEssays 2014; 36(12): 1185-1194
How do environmental factors influence life cycles and development?
Sommer F, Awazu S, Anton-Erxleben F, Jiang D, Klimovich AV, Klimovich BV, Samoilovich MP, Satou Y, Krüss M, Gelhaus C, Kürn U, Bosch TC, Khalturin K
Mol Biol Evol 2012 Oct;29(10):3081-93
Blood system formation in the urochordate Ciona intestinalis requires the variable receptor vCRL1
Development of immunoreagents for diagnostics of CagA-positive
Helicobacter pylori infections
Klimovich AV, Samoylovich MP, Gryazeva IV, Terekhina LA, Suvorov AN, Klimovich VB
Helicobacter 2010; 15(3):193-200
Book Chapters
Chapter 9: Hydra and the evolution of stem cells
in „Stem cell biology and regenerative medicine”
Klimovich A, Bosch TCG
River Publishers, Eds: Pierre Charbord and Charles Durand; 2021 ; P.207-242
Chapter 5: Hydra and the evolution of stem cells
in „Stem cell biology and regenerative medicine”
Klimovich A, Böhm AM, Bosch TCG
River Publishers, Eds: Pierre Charbord and Charles Durand; 2015 ; P.113-136